British Association for Cytopathology Scientific Meeting 9-11 October 2014 - Abstracts Non-Gynaecological Cytology Oral Session 10 October 2-3 pm Thyroid cytology-histology correlation before and after introduction of the RCPath terminology for thyroid cytology reporting

Objectives:1-To determine the Positive Predictive Value(PPV) of ?glandularNeoplasia and borderline nuclear changes in glandularcells by comparing and correlating the cytology andhistological reports. 2Compare the Positive Predictive Value(PPV) to other recent studies inLiterature. Design: Retrospective review Method: Review of the cytology and histology reports via electronic pathology recordsystem of patients reported as glandular and borderline nuclear changes in glandularcells and their subsequent histology if available over a 3 year period (2011 – 2013) inWest Kent pathology Network. Results: Group 1 ?glandular neoplasiaGroup 2 Borderline nuclear changes in glandular cellsThe PPV of group 1 was 73% compared for 75.4%,66.3%,52%.However the PPV ofclinically significant lesion was 89% compared for 80% and 81%.The PPV of group 2was 11% as compared to 24.1% and 17% and PPV of clinically significant lesion ingroup 2 is 23% as compared to 56%. Conclusion: Women with ?glandular neoplasia on cytology have a high probabilityof a glandular lesion and even higher probability of clinically significant lesion andshould be referred for colposcopy. Borderline nuclear changes in glandular cellsmight require further evaluation before referral for colposcopy.